For more than 25 years, AMRI has provided expertise in synthetic and medicinal chemistry, driven by the goal of discovering compounds for progression into human clinical trials. We deliver expert solutions for complex discovery challenges, and our track record of success demonstrated by:
- More than 200 drug discovery programs
- More than 85 preclinical and clinical candidates
- More than 240 issued patents and dozens of additional filings
Our complete suite of diverse chemistry capabilities includes:
- Integration with discovery biology and pharmacology to support hit-to-lead identification through candidate selection
- Structure activity relationships (SARs)/structure property relationships (SPRs) and novel target development guided by computer-aided drug design (CADD)
- Route design
- Custom synthesis
- Parallel synthesis
- Library design and synthesis, including AMRI’s Compound Library Consortium (diverse compound library)
- Asymmetric synthesis
- Chiral separations (analytical and preparative supercritical fluid chromatography)
- Metabolite synthesis
- Controlled substance and high-potency synthesis
- Antibody drug conjugate (ADC) expertise for novel therapeutics
- Complex chemistries including eicosanoids, polysaccharides and challenging reactions
- Global facilities in Albany and Hyderabad, India (Hyderabad Research Centre, Pvt. Ltd./AMRHRC)
Learn how our integrated drug discovery centers combine scientific expertise and leading-edge technology to accelerate innovation.