AMRI’s unique and efficient fermentation processes speed supply of natural product leads and analogs for practical, scalable processes. At our cutting-edge facilities, we adhere to cGMP fermentation procedures, ensuring process safety and product quality and purity.
Leverage our fermentation capabilities for a variety of applications, such as:
- Natural products production
- Biotransformations to complement classical chemistry
- Hydroxylations to enable new chemical routes
- Asymmetric syntheses and chiral resolutions
- Practical bioprocess development and improvement
We offer global capacity for full fermentation, semi-synthesis and enzymatic process development, including:
- More than 40,000 purified biocatalysts and strains
- Expertise with diverse strains, especially eubacteria, fungi and yeasts
- Broad experience with numerous biocatalyst classes (hydroxylating, redox, halogenating, stereoselective)
- Predetermined phylogenetic and biotransformation capabilities of biocatalysts
- Proprietary parallel mini-fermenters and bioreactors with design of experiments
- High-throughput analytical systems, including liquid chromatography/mass spectrometry (LC/MS) and chiral high-performance liquid chromatography (HPLC)
- Proven technology transfer procedures and scale-up from mL to 500 L
- Extensive downstream separations and chemistry integration