We provide a complete suite of expert structure elucidation techniques for proteins, peptides, oligonucleotides, PEGylated proteins and small molecule drugs, antibody-drug conjugates (ADCs) and other polymers:
- Mass spectrometry
- Ultra-high resolution Q-TOF mass spectrometer for accurate identification of proteins, peptides, oligonucleotides, PEGylated proteins and small molecule drugs, ADCs and other polymers in extremely small quantities
- De novo peptide sequencing and identification of modified sites using MS/MS
- High-resolution MS for accurate determination of drug-to-antibody ratio and drug load distribution of ADCs
- NMR spectroscopy
- Determination of the 3-D structures of proteins, peptides and oligonucleotides
- NMR spectrometer equipped for liquid and solid state analysis, providing comprehensive 1-D and 2-D spectra data for identification and structure determination
- Single crystal structure determination of peptides
- Services for single crystal screening and three-dimensional structure determination by X-ray diffraction
Contact our solid state services team at SSCI by clicking below