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    • Drug Discovery Solutions
      • Discovery Biology
        • Protein Expression and Purification
        • From Concept to Candidate
        • High-Throughput Screening
        • Assay Development
      • Synthetic and Medicinal Chemistry
      • In Vitro Pharmacology/DMPK
        • AMRI Express Ordering Portal
        • DMPK Assay List
        • IND-enabling Support Services
        • Drug Metabolite Identification and Synthesis
        • Bioanalysis
      • Libraries
        • AMRI Synthetic Compound Collection (ASCC)
        • Custom Chemical Library Synthesis
      • Lead Optimization
      • CADD
      • Fermentation
      • Biocatalysis and Bioprocessing
      • Catalog Compounds
      • Insourcing
    • Drug Development Solutions
      • Chemical Process R&D
        • Continuous Flow Processing
        • Custom Synthesis
        • Process Safety Assessment
        • Scale-up Capabilities
        • High-Potency APIs (HPAPIs)
      • Preformulation and Material Science
        • Physical Characterization
        • Solid Form Screening and Selection
        • Enantiomeric Resolution
        • API Process Integration
        • Bulk Characterization
      • Formulation Development
      • Separations Sciences
        • Chiral Method Development
        • Chiral Resolution
        • Chemical Purification
        • Impurity Isolation and Identification
      • Bioanalytical Services
      • Fine Chemicals
        • Fine Chemicals Catalog
        • Vinylphosphonic Acid – VPA
      • Kilo Lab and Small-Scale Manufacturing
      • Chemical Development
      • Technologies and Capabilities
        • Fermentation, Biocatalysis and Bioprocesses
        • Organometallic Chemistry
        • Propanephosphonic Acid Anhydride – T3P®
        • Vinylphosphonic Acid (VPA)
    • Analytical Services
      • Analytical Testing Services
        • Sample Submission and Forms
        • Biopharmaceutical Analysis
        • Chromatography
        • Diffraction Studies
        • Gas Testing
        • Heavy Metals Testing
        • Biochemistry Services
          • Regulatory Aspects of Biological Pharmaceuticals
          • Biochemical and Biosimilar Characterization
          • Product-Related Impurity Characterization
          • Aggregation State Characterization
          • Structure Elucidation
          • Protein Formulation Development
          • Comparability Studies
          • Analytical Method Development and Validation
          • Protein and Peptide Crystallization
        • Initial Drug Substance Characterization
        • Mass Spectrometry
        • Material Testing
        • Microbiology
        • Micromeritics
        • Microscopy
        • Personal Care Chemistry
        • Residual Solvents
        • Sorption and Desorption
        • Spectroscopy
        • Structural Characterization
        • Thermal Analysis and Calorimetry
        • Water Analysis
      • Batch Release and Stability Lot Testing
        • Method Development and Validation
      • Solid-State Chemistry and Particle Engineering
        • Solid Form Screening and Selection
        • Crystallization Process Development
        • Computational Methods
        • PAT and Pharmaceutical Quality by Design
      • Drug Product and Delivery
        • Stability, Solubility, Dissolution
        • Mapping and Imaging Studies
        • Formulation Services
      • Extractables and Leachables
        • Chemical Characterization
        • E&L for Pharma and Biotech
        • Impurities
        • Toxicological Risk Assessment (TRA)
      • Container Closure Integrity
        • Vacuum Decay Leak Detection
        • Electrical Conductivity (HVLD)
        • Helium Leak Detection (HeLD)
        • Residual Seal Force (RSF)
        • Mass Flow Leak Detection
        • Laser-Based Headspace Analysis
        • Airborne Ultrasound / Seal-Scan
      • Container Qualification
        • Pharmaceutical Glass
        • <USP 661> Plastic Containers
        • <USP 670> Auxiliary Packaging Components
        • <USP 671> Container Performance
        • EP & JP Container Testing
        • Elastomeric Closures
        • Biological Reactivity
        • Container Qualification Full Test List
      • Packaging and Distribution Testing
        • ASTM & ISTA Distribution
        • Environmental Conditioning, Cycling and Simulation Testing
        • Pharmaceutical Package Testing
        • Medical Device Packaging Testing
        • Consumer Product Packaging
        • Shelf Life and Accelerated Aging Testing
        • Packaging Materials Testing
        • Package Labeling
        • Package Strength
        • Package Integrity
        • Retains and Complaint Resolution
      • Medical Device Testing
        • Cleaning Validations
        • ISO 10993 Biocompatibility
        • ISO 11607 Medical Device Validation
        • Mechanical and Functional Device Testing
        • Leak Detection
        • Dose Delivery
        • Syringes
      • Microbiological Laboratory
        • Microbial Limits Testing
        • Bacterial Endotoxin Testing: USP <85>
        • Antimicrobial Effectiveness – AET
        • Microbiological Population Verification
        • USP <87> Biological Reactivity Tests – In Vitro
        • Disinfectant Efficacy
        • Environmental Monitoring
        • Water Testing
      • Problem Solving
        • Patent Prosecution and Litigation Support
        • Intellectual Property Support
        • Regulatory Support
        • Counterfeit Analysis
    • API Development and Manufacturing Solutions
      • APIs and Intermediates
      • Custom Synthesis and Contract Manufacturing
      • Fine Chemicals
      • Technologies and Capabilities
        • Fermentation, Biocatalysis and Bioprocesses
        • Boronic Acids, Biaryls, Grignards and Organolithiums
        • Sterile APIs
        • DEA-Controlled Compounds
        • High-Potency APIs
        • Halogenations and Other Hazardous Chemistries
        • Propanephosphonic Acid Anhydride – T3P®
        • Regulatory Support and QA
    • Drug Product Solutions
      • Drug Product Development Capabilities
      • Drug Product Manufacturing
        • Vials
        • Syringes
        • Bottles
        • Lyophilization
      • Sterile University
      • Stability and Release Testing
  • Government Contracting
    • CAS and other designations
    • Prime Contracts
    • Subcontracts
  • News & Events
    • News
    • Events
  • AMRI Express
    • In Vitro DMPK
    • Antimicrobial Discovery
  • Let’s Get Started

Publications and Patents

  • About Us
    • Company History
    • Our Purpose and Values
    • Leadership Team
    • Investor Relations
    • Global Facilities
    • Performance Metrics and Compliance
    • Contact Us
  • Solutions
    • Drug Discovery Solutions
      • Discovery Biology
        • Protein Expression and Purification
        • From Concept to Candidate
        • High-Throughput Screening
        • Assay Development
      • Synthetic and Medicinal Chemistry
      • In Vitro Pharmacology/DMPK
        • AMRI Express Ordering Portal
        • DMPK Assay List
        • IND-enabling Support Services
        • Drug Metabolite Identification and Synthesis
        • Bioanalysis
      • Libraries
        • AMRI Synthetic Compound Collection (ASCC)
        • Custom Chemical Library Synthesis
      • Lead Optimization
      • CADD
      • Fermentation
      • Biocatalysis and Bioprocessing
      • Catalog Compounds
      • Insourcing
    • Drug Development Solutions
      • Chemical Process R&D
        • Continuous Flow Processing
        • Custom Synthesis
        • Process Safety Assessment
        • Scale-up Capabilities
        • High-Potency APIs (HPAPIs)
      • Preformulation and Material Science
        • Physical Characterization
        • Solid Form Screening and Selection
        • Enantiomeric Resolution
        • API Process Integration
        • Bulk Characterization
      • Formulation Development
      • Separations Sciences
        • Chiral Method Development
        • Chiral Resolution
        • Chemical Purification
        • Impurity Isolation and Identification
      • Bioanalytical Services
      • Fine Chemicals
        • Fine Chemicals Catalog
        • Vinylphosphonic Acid – VPA
      • Kilo Lab and Small-Scale Manufacturing
      • Chemical Development
      • Technologies and Capabilities
        • Fermentation, Biocatalysis and Bioprocesses
        • Organometallic Chemistry
        • Propanephosphonic Acid Anhydride – T3P®
        • Vinylphosphonic Acid (VPA)
    • Analytical Services
      • Analytical Testing Services
        • Sample Submission and Forms
        • Biopharmaceutical Analysis
        • Chromatography
        • Diffraction Studies
        • Gas Testing
        • Heavy Metals Testing
        • Biochemistry Services
          • Regulatory Aspects of Biological Pharmaceuticals
          • Biochemical and Biosimilar Characterization
          • Product-Related Impurity Characterization
          • Aggregation State Characterization
          • Structure Elucidation
          • Protein Formulation Development
          • Comparability Studies
          • Analytical Method Development and Validation
          • Protein and Peptide Crystallization
        • Initial Drug Substance Characterization
        • Mass Spectrometry
        • Material Testing
        • Microbiology
        • Micromeritics
        • Microscopy
        • Personal Care Chemistry
        • Residual Solvents
        • Sorption and Desorption
        • Spectroscopy
        • Structural Characterization
        • Thermal Analysis and Calorimetry
        • Water Analysis
      • Batch Release and Stability Lot Testing
        • Method Development and Validation
      • Solid-State Chemistry and Particle Engineering
        • Solid Form Screening and Selection
        • Crystallization Process Development
        • Computational Methods
        • PAT and Pharmaceutical Quality by Design
      • Drug Product and Delivery
        • Stability, Solubility, Dissolution
        • Mapping and Imaging Studies
        • Formulation Services
      • Extractables and Leachables
        • Chemical Characterization
        • E&L for Pharma and Biotech
        • Impurities
        • Toxicological Risk Assessment (TRA)
      • Container Closure Integrity
        • Vacuum Decay Leak Detection
        • Electrical Conductivity (HVLD)
        • Helium Leak Detection (HeLD)
        • Residual Seal Force (RSF)
        • Mass Flow Leak Detection
        • Laser-Based Headspace Analysis
        • Airborne Ultrasound / Seal-Scan
      • Container Qualification
        • Pharmaceutical Glass
        • <USP 661> Plastic Containers
        • <USP 670> Auxiliary Packaging Components
        • <USP 671> Container Performance
        • EP & JP Container Testing
        • Elastomeric Closures
        • Biological Reactivity
        • Container Qualification Full Test List
      • Packaging and Distribution Testing
        • ASTM & ISTA Distribution
        • Environmental Conditioning, Cycling and Simulation Testing
        • Pharmaceutical Package Testing
        • Medical Device Packaging Testing
        • Consumer Product Packaging
        • Shelf Life and Accelerated Aging Testing
        • Packaging Materials Testing
        • Package Labeling
        • Package Strength
        • Package Integrity
        • Retains and Complaint Resolution
      • Medical Device Testing
        • Cleaning Validations
        • ISO 10993 Biocompatibility
        • ISO 11607 Medical Device Validation
        • Mechanical and Functional Device Testing
        • Leak Detection
        • Dose Delivery
        • Syringes
      • Microbiological Laboratory
        • Microbial Limits Testing
        • Bacterial Endotoxin Testing: USP <85>
        • Antimicrobial Effectiveness – AET
        • Microbiological Population Verification
        • USP <87> Biological Reactivity Tests – In Vitro
        • Disinfectant Efficacy
        • Environmental Monitoring
        • Water Testing
      • Problem Solving
        • Patent Prosecution and Litigation Support
        • Intellectual Property Support
        • Regulatory Support
        • Counterfeit Analysis
    • API Development and Manufacturing Solutions
      • APIs and Intermediates
      • Custom Synthesis and Contract Manufacturing
      • Fine Chemicals
      • Technologies and Capabilities
        • Fermentation, Biocatalysis and Bioprocesses
        • Boronic Acids, Biaryls, Grignards and Organolithiums
        • Sterile APIs
        • DEA-Controlled Compounds
        • High-Potency APIs
        • Halogenations and Other Hazardous Chemistries
        • Propanephosphonic Acid Anhydride – T3P®
        • Regulatory Support and QA
    • Drug Product Solutions
      • Drug Product Development Capabilities
      • Drug Product Manufacturing
        • Vials
        • Syringes
        • Bottles
        • Lyophilization
      • Sterile University
      • Stability and Release Testing
  • Government Contracting
    • CAS and other designations
    • Prime Contracts
    • Subcontracts
  • News & Events
    • News
    • Events
  • AMRI Express
    • In Vitro DMPK
    • Antimicrobial Discovery
  • Let’s Get Started

Selected Publications and Patents

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  • Contact Us
  • Careers
  • Customer Care
  • Resource Library
  • Client Login
  • About Us
    • Company History
    • Our Purpose and Values
    • Leadership Team
    • Investor Relations
    • Global Facilities
    • Performance Metrics and Compliance
    • Contact Us
  • Solutions
    • Drug Discovery Solutions
      • Discovery Biology
        • Protein Expression and Purification
        • From Concept to Candidate
        • High-Throughput Screening
        • Assay Development
      • Synthetic and Medicinal Chemistry
      • In Vitro Pharmacology/DMPK
        • AMRI Express Ordering Portal
        • DMPK Assay List
        • IND-enabling Support Services
        • Drug Metabolite Identification and Synthesis
        • Bioanalysis
      • Libraries
        • AMRI Synthetic Compound Collection (ASCC)
        • Custom Chemical Library Synthesis
      • Lead Optimization
      • CADD
      • Fermentation
      • Biocatalysis and Bioprocessing
      • Catalog Compounds
      • Insourcing
    • Drug Development Solutions
      • Chemical Process R&D
        • Continuous Flow Processing
        • Custom Synthesis
        • Process Safety Assessment
        • Scale-up Capabilities
        • High-Potency APIs (HPAPIs)
      • Preformulation and Material Science
        • Physical Characterization
        • Solid Form Screening and Selection
        • Enantiomeric Resolution
        • API Process Integration
        • Bulk Characterization
      • Formulation Development
      • Separations Sciences
        • Chiral Method Development
        • Chiral Resolution
        • Chemical Purification
        • Impurity Isolation and Identification
      • Bioanalytical Services
      • Fine Chemicals
        • Fine Chemicals Catalog
        • Vinylphosphonic Acid – VPA
      • Kilo Lab and Small-Scale Manufacturing
      • Chemical Development
      • Technologies and Capabilities
        • Fermentation, Biocatalysis and Bioprocesses
        • Organometallic Chemistry
        • Propanephosphonic Acid Anhydride – T3P®
        • Vinylphosphonic Acid (VPA)
    • Analytical Services
      • Analytical Testing Services
        • Sample Submission and Forms
        • Biopharmaceutical Analysis
        • Chromatography
        • Diffraction Studies
        • Gas Testing
        • Heavy Metals Testing
        • Biochemistry Services
          • Regulatory Aspects of Biological Pharmaceuticals
          • Biochemical and Biosimilar Characterization
          • Product-Related Impurity Characterization
          • Aggregation State Characterization
          • Structure Elucidation
          • Protein Formulation Development
          • Comparability Studies
          • Analytical Method Development and Validation
          • Protein and Peptide Crystallization
        • Initial Drug Substance Characterization
        • Mass Spectrometry
        • Material Testing
        • Microbiology
        • Micromeritics
        • Microscopy
        • Personal Care Chemistry
        • Residual Solvents
        • Sorption and Desorption
        • Spectroscopy
        • Structural Characterization
        • Thermal Analysis and Calorimetry
        • Water Analysis
      • Batch Release and Stability Lot Testing
        • Method Development and Validation
      • Solid-State Chemistry and Particle Engineering
        • Solid Form Screening and Selection
        • Crystallization Process Development
        • Computational Methods
        • PAT and Pharmaceutical Quality by Design
      • Drug Product and Delivery
        • Stability, Solubility, Dissolution
        • Mapping and Imaging Studies
        • Formulation Services
      • Extractables and Leachables
        • Chemical Characterization
        • E&L for Pharma and Biotech
        • Impurities
        • Toxicological Risk Assessment (TRA)
      • Container Closure Integrity
        • Vacuum Decay Leak Detection
        • Electrical Conductivity (HVLD)
        • Helium Leak Detection (HeLD)
        • Residual Seal Force (RSF)
        • Mass Flow Leak Detection
        • Laser-Based Headspace Analysis
        • Airborne Ultrasound / Seal-Scan
      • Container Qualification
        • Pharmaceutical Glass
        • <USP 661> Plastic Containers
        • <USP 670> Auxiliary Packaging Components
        • <USP 671> Container Performance
        • EP & JP Container Testing
        • Elastomeric Closures
        • Biological Reactivity
        • Container Qualification Full Test List
      • Packaging and Distribution Testing
        • ASTM & ISTA Distribution
        • Environmental Conditioning, Cycling and Simulation Testing
        • Pharmaceutical Package Testing
        • Medical Device Packaging Testing
        • Consumer Product Packaging
        • Shelf Life and Accelerated Aging Testing
        • Packaging Materials Testing
        • Package Labeling
        • Package Strength
        • Package Integrity
        • Retains and Complaint Resolution
      • Medical Device Testing
        • Cleaning Validations
        • ISO 10993 Biocompatibility
        • ISO 11607 Medical Device Validation
        • Mechanical and Functional Device Testing
        • Leak Detection
        • Dose Delivery
        • Syringes
      • Microbiological Laboratory
        • Microbial Limits Testing
        • Bacterial Endotoxin Testing: USP <85>
        • Antimicrobial Effectiveness – AET
        • Microbiological Population Verification
        • USP <87> Biological Reactivity Tests – In Vitro
        • Disinfectant Efficacy
        • Environmental Monitoring
        • Water Testing
      • Problem Solving
        • Patent Prosecution and Litigation Support
        • Intellectual Property Support
        • Regulatory Support
        • Counterfeit Analysis
    • API Development and Manufacturing Solutions
      • APIs and Intermediates
      • Custom Synthesis and Contract Manufacturing
      • Fine Chemicals
      • Technologies and Capabilities
        • Fermentation, Biocatalysis and Bioprocesses
        • Boronic Acids, Biaryls, Grignards and Organolithiums
        • Sterile APIs
        • DEA-Controlled Compounds
        • High-Potency APIs
        • Halogenations and Other Hazardous Chemistries
        • Propanephosphonic Acid Anhydride – T3P®
        • Regulatory Support and QA
    • Drug Product Solutions
      • Drug Product Development Capabilities
      • Drug Product Manufacturing
        • Vials
        • Syringes
        • Bottles
        • Lyophilization
      • Sterile University
      • Stability and Release Testing
  • Government Contracting
    • CAS and other designations
    • Prime Contracts
    • Subcontracts
  • News & Events
    • News
    • Events
  • AMRI Express
    • In Vitro DMPK
    • Antimicrobial Discovery
  • Let’s Get Started