June 25, 2018
Assay System:
- Liver microsomes
Assay Conditions:
| Test Compound Concentration | 50 µM |
| Incubation Time | 3 hours |
| pH | 7.4 |
| Temperature | 37 °C |
| Positive Control | Clozapine |
| Analysis | LC-MS/MS |
| Number of Repeats | 2 |
Deliverable: Molecular weights and relative abundance of detected conjugates of test compound with glutathione or KCN. Tentative structures of conjugates determined using MS/MS analysis are available upon request.
Test Compound Requirement: 1-2 mg dry powder or 100-200 µL of 10 mM DMSO stock solution.